Supportive Criteria (EFNS/PNS)

Carol L. Koski, M.D. and Richard A. Lewis, M.D., Principal Authors

Information adapted from Joint Task Force of the EFNS and the PNS, 2005

1. Elevated cerebrospinal fluid protein with leukocyte <10/mm3 (level A recommendation)
2. Magnetic resonance imaging showing gadonlinium enhancement and /or hypertrophy of the cauda equine, lumbosacral or cervical nerve roots, or the brachial or lumbosacral plexus (level C recommendation)
3. Nerve biopsy showing unequivocal evidence of demyelination and/or remyelination in >5 fibers by electron microscopy or in >6 of 50 teased fibers
4. Clinical improvement following immunomodulatory treatment (level A recommendation)